Please note that the final data for overdose deaths in 2021 was just released, and can be found on the CDC website here https://www.cdc.gov/nchs/pressroom/default.htm. Key findings indicate that the age-adjusted rate of drug overdose deaths rose more than 14% from 2020 through 2021 in the United States, and  synthetic opioids and polysubstance use continue to drive the worsening crises. The National Center for Health Statistics briefs can be found below:

• Mortality in the United States, 2021

• Drug Overdose Deaths in the United States, 2001–2021